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Understanding diabetic retinopathy, a condition that affects millions worldwide, is the first step in managing and preventing vision loss from this disease. Diabetic retinopathy is a diabetes complication that affects the eyes. It's caused by damage to the blood vessels of the light-sensitive tissue at the back of the eye (retina). The progression of this disease can be slow and asymptomatic, leading to significant eye damage before the person is even aware of the problem.